Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Viagra has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.
Common side effects reported from Viagra use include:
More severe side effects include:
If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.
As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Viagra. Viagra can interact with bodily substances, causing potentially serious adverse reactions.
Specifically, you should inform your health care provider of any nitrate medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.
In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.
asthma in men (Alli)As with most medications, Viagra can cause a dangerous drop in blood pressure. The chance is small, but if you take Viagra and have heart problems, you should consult with your health care provider immediately.
In addition, inform your health care provider if you have experienced liver or kidney disease, low levels of potassium in your blood, or heart disease.
If you experience severe dizziness, fainting, or heart attack, get medical attention immediately. Other side effects can include swelling, redness, and shortness of breath. These effects are relatively rare, and should be treated with careful planning.
If you experience symptoms of an allergic reaction, seek medical attention immediately. Symptoms can include:
As with any medication, Viagra can cause you to feel pain during sex. This pain is similar to what’s caused by a cold, cough, or other physical reaction. If you experience these symptoms, contact your health care provider.
If you experience any severe skin reactions, contact your health care provider immediately. These effects are relatively rare and should be treated with caution.
If you experience any new or worsening symptoms, contact your health care provider immediately. These conditions can include:
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pill for low blood pressureAs an educational resource, Healthline and the Mayo Clinic are not affiliated with The A. Online Pharmacy, Inc.
buy Viagra without a prescriptionViagra is available without a prescription at aphysician’s cost, but it is typically notfor everyone. Viagra is a prescription medication, so it will depend on your specific needs. Be sure to tell your pharmacist about all your current medications, supplements, and herbal treatments.
Viagra is manufactured by Pfizer.
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Viagra Connect is a prescription medicine used to treat erectile dysfunction (ED). It works by increasing blood flow to the penis. This helps men to get or maintain an erection.
Viagra Connect contains sildenafil, which belongs to a group of medicines known as phosphodiesterase type 5 (PDE5) inhibitors. Viagra Connect is used to treat erectile dysfunction (ED).
Viagra Connect should be taken orally with a glass of water. It is important to swallow the tablet whole with water, and to not crush, chew or break it. If you have trouble swallowing Viagra Connect, it can be used by mistake.
You should swallow the tablet whole with water, and not crush, chew or break it.
Avoid alcohol during treatment with Viagra Connect as it may increase the side effects of the medicine.
If you are taking a medicine containing sildenafil, you should not take Viagra Connect before having sex. This medicine is not for use before or after sex.
You should not take Viagra Connect if you are allergic to sildenafil or any of the other ingredients of this medicine.
Viagra Connect comes in the form of a tablet, and should be taken orally with a glass of water. It is important to swallow the tablet whole with water, and to not crush, chew, or break it.
Viagra Connect is usually taken as needed before sexual activity. You should take Viagra Connect with a glass of water as this can help avoid stomach upset. Do not take Viagra Connect more than once a day. If you have any questions or concerns about taking Viagra Connect, talk with your doctor or pharmacist.
If you have been prescribed Viagra Connect by a doctor or a specialist, you should tell them about your treatment before you start using Viagra Connect. This includes medical advice and tests.
Viagra Connect is available in the form of a tablet. It contains sildenafil, which belongs to a group of medicines called PDE5 inhibitors. These medicines work by relaxing the blood vessels in your penis. This allows blood to flow into the penis when you are sexually stimulated.
Viagra Connect is only for use by men under the age of 18. It should not be taken by women or children.
Viagra Connect is usually taken about 30 minutes before you plan to have sex. You should take Viagra Connect with a glass of water, and to avoid stomach upset, do not take Viagra Connect after a heavy meal.
Viagra Connect is not suitable for use by women or children.
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Viagra generic entryThe story of Viagra’s patents and generic entry of sildenafil citrate is a valuable one because it covers many of the nuances of drug patenting and generic entry in the United States.
This article will describe the multiple patents, patent term extension, pediatric extension, litigation, out-of-court-settlement, and authorized generic fighter brand elements which led to Viagra’s long patent life and limited early entry of generics, and Pfizer’s post generic-entry strategy to limit the impact of competitors.
was approved in 1998, and the original patent covering Viagra was, which received a 283-day patent term extension giving it an expiration date of March 29th, 2012. This 14-year patent life is longer than many other drugs, but Pfizer was able extend the patent-protected life even further.
The ‘534 patent was filed in 1990, and in 1994 (four years prior to Viagra’s launch) Pfizer filed a second patent:. Because the ‘012 patent was filed prior to June 8th 1995 its term is17 years from the grant date, rather than20 years from the filing date, which is how expiration is determined for patents filed after Jun 8th 1995. The ‘012 patent was granted on October 22nd, 2002, so the original expiration date was set to October 22nd, 2019 — more than twenty years after the drug’s launch. The patent’s expiration was extended to April 22nd 2020 because Pfizer responded to an FDA request to perform pediatric clinical trials, granting six months of “” protection.
Pfizer successfully defended Viagra’s patents in many over the years, but one lawsuit stands out. Despite prevailing in awhich affirmed the validity of patent 6,469,012, in 2013 Pfizer announced an, granting Teva a license to manufacture and sell genericstarting in December 2017, more than two years before Viagra’s patent expiration. Importantly, this was not a ‘‘ patent settlement, as Teva was required to pay Pfizer a licensing fee to produce the generic.
Generic drugs sell at a discount to the branded version, which hurts branded revenues, but there are things which brands can do to limit the impact. A popular tactic it to launch an. In this strategy the branded firm licenses a third party to market the branded drug under another name, compelling the generic entrant (in this case Teva) to compete in the generic market. The authorized generic for Viagra was and it was.
Viagra’s 2016 US sales were approximately 1.2 billion, and in 2017 they dropped to less than $800 million. With increased competition from Teva and from Revatio, revenues are expected to keep dropping, and widespread generic competition from the many companies with will further-decrease Viagra sales. It appears that Pfizer is responding to increased competition by increasing Viagra’s price — the has been a general increase over time.
The story of Viagra and the generic entry of sildenafil citrate illustrates the value of data and the need to continuously re-evaluate factors affecting generic entry. Reliance on the first patent would have vastly under-estimated the date of generic entry, and looking solely at the expiration date of the second patent would have missed the December 2017 generic entry. DrugPatentWatch offers the tools to continuously track patents covering drugs, litigations, tentative generic approvals, and other factors essential to making better decisions. For more information, and learn more about our.
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